Adverse Events After Pediatric Oral Sedation for Dental Procedures

Oral midazolam was 11 times less likely to result in minor postdischarge adverse events than oral chloral hydrate.

Investigators compared postdischarge adverse events in children who received either chloral hydrate (70 or 100 mg/kg; maximum, 2 g) or midazolam (1.0 or 1.5 mg/kg; maximum, 20 mg) for outpatient dental treatment sedation at a Brazilian dental sedation center. Adverse events were reported by caregivers the day after sedation. Children were included if they were categorized as American Society of Anesthesiologists class 1 or 2 and were excluded if they had Mallampati scores of 3 or 4, large tonsils, or snoring history.

Among 42 children (mean age, 3.6 years; age range, 1–8 years) who underwent 103 sedations, there were 9 minor intraoperative adverse events (hallucinations, emesis, hiccups, irritation, and desaturation not requiring supplementa…

Reviewing Author

Katherine Bakes, MD

Disclosures

RoyaltiesEmergency Medicine Secrets (Elsevier)

Grant/Research SupportDepartment of Justice

Editorial BoardsEmergency Medicine Secrets (Elsevier); Rosen’s Emergency Medicine (Elsevier)

Katherine Bakes, MD

Disclosures

RoyaltiesEmergency Medicine Secrets (Elsevier)

Grant/Research SupportDepartment of Justice

Editorial BoardsEmergency Medicine Secrets (Elsevier); Rosen’s Emergency Medicine (Elsevier)