Alternative Guidance on Dyslipidemia

Clinical Takeaway

: The VA/DoD dyslipidemia guideline differs in significant ways from the ACC/AHA guideline, highlighting room for interpretation of the clinical evidence.

An overview of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for Lipid Management for Cardiovascular Disease Risk Reduction

Background

The U.S. Department of Veterans Affairs and Department of Defense (VA/DoD) released their new guideline on dyslipidemia online in 2025, and a summary was published recently in Annals of Internal Medicine. The guideline explicitly is intended for adults “who are eligible for care in the VA and/or DOD healthcare systems.” However, readers who don’t practice in the VA/DoD systems will still find it instructive, especially with respect to areas in which it differs from the recent dyslipidemia guideline from the American College of Cardiology and American He…

Reviewing Author

Christopher W. Goodman, M.D.

Disclosures

Grant Recipient/Research SupportHealth Resources and Services Administration; NIH