Clinical Presentation of Community-Acquired MRSA Pneumonia

A small case series demonstrated milder disease and better outcomes than in previous studies, and no association with influenza.

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections present as skin abscesses or — rarely — as severe pneumonia. In the U.S., such infections are usually caused by the USA300 or the USA400 strain. These strains often produce the Panton-Valentine leukocidin (PVL) toxin; although resistant to the β-lactams and macrolides, they are usually susceptible to trimethoprim-sulfamethoxazole and clindamycin.

To investigate the clinical presentation and treatment of CA-MRSA pneumonia, researchers in Chicago performed a retrospective review of patients admitted to their institution with this illness from January 2005 through April 2007. Susceptibility of MRSA isolates to clindamycin and trimethoprim-sulfamethoxazole was us…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Clinical Presentation of Community-Acquired MRSA Pneumonia

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Reviewing Author