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Clinical Takeaway
: Patients in a registry who had discontinued anticoagulation by 6 months were no more likely to have ischemic events and were less likely to bleed.Context
Patients with atrial fibrillation (AF) who discontinued anticoagulants 1 year after ablation had better outcomes than those who continued the drugs in both the ALONE-AF trial and the OCEAN trial. To provide more data on the risks of discontinuing oral anticoagulation after ablation, researchers analyzed a prospective registry, including more than 13,600 patients who had no AF recurrence for 3 months after ablation.
Key Results
As of 6 months after ablation, about 11,000 of the patients had discontinued oral anticoagulation while more than 2600 continued. Patients with higher stroke risk (CHA2Ds2-Va score) were more likely to continue anticoagulation.
During a median 4 years of follow-up, continued oral anticoagulation at 6 months was no…