Covid during Pregnancy: Does Vaccination Help?

Clinical Takeaway

: Vaccination was associated with lower risks for severe infection and preterm birth in a large retrospective study.

Context

In 2025, the U.S. CDC removed its recommendation that pregnant and lactating women receive vaccination against Covid-19. ACOG and other medical organizations continue to recommend vaccination against Covid for all women who are pregnant, contemplating pregnancy, or lactating. Now, a study clarifies the effect of vaccination on maternal and perinatal outcomes associated with Covid during pregnancy.

Using Canadian surveillance data, researchers identified 20,000 pregnant individuals (72% vaccinated) who received diagnoses of Covid between April 2021 and December 2022 (a period that included Delta and Omicron variants) and compared outcomes based on vaccination status prior to Covid diagnosis.

Key Results

In the Delta period, Covid-associa…

Reviewing Author

Molly S. Brett, M.D.

Disclosures

Nothing to disclose