CPAP vs. Mandibular Advancement Device for Obstructive Sleep Apnea

Adherence and some quality-of-life measures were better with the device than with continuous positive airway pressure.

Comparative studies of oral appliances and continuous positive airway pressure (CPAP) to treat obstructive sleep apnea (OSA) generally have been small, with various limitations. In this randomized crossover trial that involved 126 OSA patients, Australian researchers compared CPAP with a mandibular advancement device that is adjusted gradually to the maximal comfortable limit. Sleep apnea was mild, moderate, and severe in 18%, 55%, and 27% of patients, respectively. Each modality was used for 1 month.

The mean baseline apnea-hypopnea index (AHI) was 26 events per hour. AHI decreased markedly in both the CPAP and device groups, but mean on-treatment AHI was significantly lower with CPAP (5 vs. 11 events/hour), and the proportion of patients w…

Reviewing Author

Allan S. Brett, MD

Disclosures

Nothing to disclose

Allan S. Brett, MD

Disclosures

Nothing to disclose