Does Chamomile Calm Your Nerves?

Despite growing interest in and use of alternative herbal medications in the U.S., especially for depression and anxiety, few randomized controlled trials have evaluated their efficacy. In this double-blind, placebo-controlled trial, researchers examined the efficacy of 8 weeks of treatment with chamomile extract, a traditional herbal remedy with putative calming and relaxing effects. The 57 patients had at least mild generalized anxiety disorder (Hamilton Rating Scale for Anxiety [HAM-A] minimum baseline score, 9; mean, 15) and no major comorbidities, although minor depression was allowed. The placebo was masked with a drop of chamomile oil.

Active chamomile treatment began at 220 mg and progressed to 1100 mg if tolerated; administration wa…