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Molluscum contagiosum (MC) may be benign, but it can be pruritic; become irritated, eczematized, or unsightly; and persist for several years before abating. No ideal treatment exists. Cryotherapy, trichloroacetic acid, and curettage can be painful and frightening for children. Cantharidin, readily available in Canada, is useful but difficult to access in the U.S. Imiquimod is a topical immune-response modifier that stimulates the cellular immune response, leading to local antiviral and antitumor effects. It is licensed for the local treatment of genital warts in adults. Investigators in this open-label study used 5% imiquimod cream in 15 children aged 4 to 11 years who had 3 to 55 MC lesions on areas other than the face or genitals. Imiquim…