Peter Roy-Byrne, M.D., is a Professor in the Department of Psychiatry and Behavioral Sciences at the University of Washington, Seattle. His research has emphasized health-service outcomes within both academic and community care environments, especially services at the conjunction of general medicine and psychiatry. Recent investigations have included primary-care multimodal interventions for panic, generalized anxiety, social anxiety, and post-traumatic stress and substance use disorders; preference-based treatment for post-traumatic stress disorder (PTSD) using both exposure therapy and medication; and epigenetic changes associated with major depression in discordant monozygotic twins. His past research has focused on the phenomenology and neurobiology of mood and anxiety disorders, especially the role of the benzodiazepine receptor in mood and anxiety disorders. Clinically, Dr. Roy-Byrne specializes in the evaluation, pharmacotherapy, and psychotherapy of patients with complex and treatment-refractory mood and anxiety disorders, with a focus on panic disorder, PTSD, major depression, and bipolar II disorder. He is Past President of the Society for Biological Psychiatry, Past Editor in Chief of Depression and Anxiety, Co-Editor-in-Chief, UpToDate Psychiatry, and the author of more than 400 peer-reviewed papers.