Is It Eosinophilic Esophagitis or Reflux Disease?

A predictive model reliably distinguished EoE from GERD.

Eosinophilic esophagitis (EoE) and gastroesophageal reflux disease (GERD) share many symptoms. However, distinguishing between the two conditions is critical because the management and prognosis of each differ considerably.

To identify features that differentiate EoE from GERD, researchers conducted a retrospective, single-center, case-control study involving 151 patients with EoE, defined as biopsy showing ≥15 eosinophils in at least one high-power field and at least one symptom of esophageal dysfunction (dysphagia, food impaction, heartburn, or food intolerance). Also included were 226 controls with GERD, defined by endoscopic findings of erosive or nonerosive esophagitis and at least one reflux symptom (heartburn, regurgitation, pain, or …

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors