Erythema Nodosum and Pyoderma Gangrenosum in Inflammatory Bowel Disease

Prevalence in patients with IBD was significantly associated with sex, race, and comorbid conditions.

Patients with pyoderma gangrenosum (PG) often have inflammatory bowel disease (IBD; prevalence, 10%–25% in various studies). IBD is also reported in patients with erythema nodosum (EN), although less frequently (<5%); in these patients, the skin disease appears to mirror the activity of the underlying bowel disease. The prevalence and implication of EN and PG in patients with IBD are less well known.

Investigators studied the prevalence and consequences of PG and EN in 2402 patients with IBD at one French center. Of these patients, 5.8% had at least one skin manifestation. EN was present in 4% of patients, PG in only 0.75%. EN was significantly more common in women; it was significantly and independently associated with Crohn disease, ocular…

Reviewing Author

Jeffrey P. Callen, MD

Disclosures

Consultant / Advisory board XOMA; Eli Lilly; Celgene

Equity Various trust accounts

Editorial boards JAMA Dermatology; UpToDate

Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)

Jeffrey P. Callen, MD

Disclosures

Consultant / Advisory board XOMA; Eli Lilly; Celgene

Equity Various trust accounts

Editorial boards JAMA Dermatology; UpToDate

Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)