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Chronic pain is one of the most frustrating clinical problems in primary care. Analgesics and other medications offer limited long-term benefit and have many potential adverse effects. Guidelines routinely recommend nonpharmacologic interventions, but clinicians might be unfamiliar with specific modalities that work for different pain conditions, and some evidence-based treatments involve structured programs that can be costly or otherwise challenging to access.
For busy clinicians or uncertain patients, relatively simple nonpharmacologic pain treatments are most appealing. Several 2025 studies offered promising evidence for such options:
A network meta-analysis of different exercise modalities for knee osteoarthritis (OA) showed that aerobic…
