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Acute annular urticaria (ring-shaped hives) is a benign cutaneous hypersensitivity reaction that occurs frequently in childhood. The condition is sometimes mistaken for other ring-shaped disorders — most often, erythema multiforme and less commonly, serum-sickness–like reactions.
To better distinguish the clinical features of this condition from the features of erythema multiforme and serum-sickness–like reaction, and to increase awareness of this diagnosis, pediatric dermatologists at a large children’s hospital characterized the disease in a case series of 18 children.
Most of the patients (83%) were 2 months to 3 years of age. The most common referring diagnosis was “rash” or “erythema multiforme.” A majority (67%) presented with anteceden…