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Much has been written about the role of gastroesophageal reflux disease (GERD) in the pathogenesis of “noncardiac” chest pain, but GERD has also been linked to disturbances in cardiac rhythm. In the proposed pathophysiologic mechanism behind this link, an irritant esophagogastric stimulus induces an alteration in the cardiac conduction signaling or autonomic modulation of the heart rate, resulting in cardiac dysrhythmia. Good evidence suggests that mechanical, electrical, and chemical stimulation of the esophagus can alter the balance between vagal and sympathetic activities. Investigators in Naples, Italy, assessed the relation between acid reflux in the esophagus and neurocardiac function in patients with supraventricular arrhythmias. The…