Loading...
External anogenital warts (condylomata acuminata), a manifestation of human papillomavirus (HPV) infection, is one of the most common sexually transmitted diseases. None of the topical therapies (e.g., imiquimod cream, podophyllotoxin cream, trichloroacetic acid) or surgical techniques in current use are ideal, and all are associated with painful side effects and recurrence. To determine the efficacy of topical sinecatechin ointment (Veregen) — an extract of green leaves of Camellia sinensis, composed mainly of tea polyphenols — investigators with manufacturer support conducted a multicenter, randomized, double-blind, phase III trial.
A total of 495 adult patients (254 men) received one of two strengths of sinecatechin ointment (10% or 15%) …