Growing Hair with Botox

Botulinum toxin A (BTX A) has been used for the treatment of wrinkles, hyperhidrosis, and headaches. Now, here comes an open-label pilot study from Canada of BTX A to treat androgenic alopecia. The study was supported by an educational grant from the manufacturer, and the authors hold intellectual property rights to the treatment process.

Fifty males with Norwood/Hamilton alopecia classes II to IV had injections to the scalp muscles (divided equally to the frontalis, temporalis, periauricular, and occipitalis) of a total of 150 units of BTX A, followed by a second session 24 weeks later. Assessment included change in hair counts in a 2-cm scalp area, changes in hair loss counts collected by lint roller from the subject's pillow, and patient responses to a questionnaire. The 60-week study period consisted of a 12-week baseline lead-in period and two 24-week treatment periods following each BTX A treatment session.

In the 40 patients who completed the study, mean hair counts increased 18% from baseline to 48 weeks after the initial injection, a statistically significant change. Hair loss was also significantly reduced, by a mean of 39%. The reduction in hair loss and increase in hair counts were not correlated. The treatment response rate was 75%. The subjects noted statistically significant increased hair growth. No adverse events were noted.