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Epidemiologic evidence suggests that HIV-infected people remain at higher than usual risk for “ordinary” illnesses even if their HIV infection is optimally controlled. Now, investigators describe patterns of biochemical markers that seem to bolster such evidence.
Baseline serum samples from a subset of HIV-infected individuals in the SMART study were compared with samples from adults participating in two large U.S. cohort studies meant to represent the general population. Overall, HIV-infected individuals had significantly worse lipid profiles and were more likely to be receiving lipid-lowering and antihypertensive drugs. After adjustment for these differences and for age, sex, and race, HIV-infected individuals had significantly higher leve…