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Lichen aureus (LA) presents as stable, golden brown lesions, usually on the legs, that can persist for years. This disease belongs to the group of persistent pigmented purpuric dermatoses (PPPD) with a dense lichenoid lymphocytic infiltrate and siderophages. An association between PPPD and mycosis fungoides (MF) has been reported. Looking for such a link, investigators retrospectively studied 23 patients (mean age, 47) diagnosed with LA in the dermatology department of the Medical University of Graz.
The authors reviewed clinical information and analyzed T-cell gene rearrangements when tissue was available. At the time of the study, a mean of 102 months after diagnosis, only seven patients had stable lesions. Two of the 23 patients had died …