A Link Between Eosinophilic Esophagitis and Celiac Disease?

In a case series of 17 children with EoE, 6 had celiac disease; after switching to gluten-free diets, all 6 had complete resolution of their presenting EoE complaints.

Eosinophilic esophagitis (EoE) is an inflammatory disorder that is characterized by severe, isolated eosinophilic infiltration of the esophagus; it is associated with a variety of clinical findings, including dysphagia, food impaction, vomiting, chest pain, and weight loss (Journal Watch Gastroenterology Mar 28 2006). Although its causes are unknown, EoE has been linked to food hypersensitivity, particularly among children. In fact, the primary approach for treating pediatric EoE is elimination diets, which typically exclude cow’s milk, soy, wheat, eggs, peanuts, and seafood (Journal Watch Gastroenterology Jan 5 2007). Now, investigators describe a possible association between EoE and celiac disease.

During a 21-month period at a single cent…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors