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Johnson & Johnson is reducing the maximum daily dose of Extra-Strength Tylenol from 4000 mg to 3000 mg (eight to six pills) to help lower the risk for overdose. The change will appear on the drug's label beginning in the fall.
The manufacturer says that it will also lower the maximum daily dose for regular-strength Tylenol and other drugs containing acetaminophen in 2012.
The change is in line with the advice of an FDA working group that in 2009 recommended limiting the maximum adult daily dose to about 3000 mg in an attempt to decrease liver damage from the drug.
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LINK(S):
Manufacturer news release (Free)
Physician's First Watch coverage of 2009 recommendation (Free)