Dark patches on the extensor surfaces of extremities are characteristic for drug-induced skin changes, particularly tetracyclines like the minocycline prescribed to this patient for her rosacea. Cutaneous and oral involvement can occur regardless of dose or duration, and deposition in other organs typically follows prolonged use. While usually reversible upon drug discontinuation, pigmentation may become permanent with long-term use — so there’s no need to get blue if caught early.
Comment
Dark patches on the extensor surfaces of extremities are characteristic for drug-induced skin changes, particularly tetracyclines like the minocycline prescribed to this patient for her rosacea. Cutaneous and oral involvement can occur regardless of dose or duration, and deposition in other organs typically follows prolonged use. While usually reversible upon drug discontinuation, pigmentation may become permanent with long-term use — so there’s no need to get blue if caught early.