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By Amy Orciari Herman
Edited by Richard Saitz, MD, MPH, FACP, DFASAM
A research group proposes extending the screening interval for diabetic retinopathy in low-risk patients with type 1 diabetes. Currently, annual exams are recommended.
The researchers followed 1400 people with type 1 diabetes for nearly 30 years. Fundus photography was performed every 6 months during for the first 10 years, then every 4 years thereafter. Some 24,000 retinopathy examinations were performed.
Changes in patients' exam results were analyzed throughout follow-up to estimate the odds of progression to proliferative diabetic retinopathy. Based on their findings, the researchers suggest the following screening schedule according to a patient's retinopathy state:
State 1 — no retinopathy — screen every 4 years
State 2 — mild nonproliferative retinopathy — every 3 years
State 3 — moderate nonproliferative retinopathy — every 6 months
State 4 — severe nonproliferative retinopathy — every 3 months
Increasing glycated hemoglobin levels would warrant more frequent screening.
In the New England Journal of Medicine, the authors say their screening schedule would save $1 billion over 20 years. Editorialists, meanwhile, note that the schedule could lower screening rates too much.
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LINK(S):
NEJM article (Free abstract)
NEJM editorial (Subscription required)
Researchers' web app to calculate appropriate screening interval based on retinopathy state and HbA1c (Free)