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By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
Have a look at some of the latest developments on novel coronavirus disease (COVID-19):
Neutralizing antibody: Researchers report the first human monoclonal antibody, known as 47D11, that neutralizes SARS-CoV-2 infection in vitro. They note in Nature Communications that 47D11 did not block the virus through receptor-binding interference; rather, the mechanism is currently unknown. They say the antibody "will be useful for development of antigen detection tests and serological assays targeting SARS-CoV-2."
Reopening physician practices: The American Medical Association has published a guide for clinicians about reopening their medical practices. It includes information on screening patients for COVID-19 before their in-person visits.
Projections for U.S. deaths: New government models predict that U.S. COVID-19 deaths could hit 3000 a day by June, the New York Times reports. Currently, about 1750 people are dying every day. The models predict 200,000 new cases a day. There are currently about 25,000 new daily cases.
Antibody tests: The FDA is requiring companies with antibody tests for SARS-CoV-2 to submit their data validating the tests' accuracy within 10 days.
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LINK(S):
Nature Communications article on neutralizing antibodies (Free)
AMA guide to reopening physician practices (Free)
New York Times story on U.S. deaths (Free)
FDA notice on antibody tests (Free)
NEJM Journal Watch COVID-19 page (Free)
NEJM COVID-19 page (Free)