NIH Updates COVID-19 Treatment Guidelines

By Kelly Young

Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS

The National Institutes of Health has made significant updates to its guidelines on treating people with COVID-19. Among the changes:

• There is not enough evidence to recommend for or against the use of colchicine in nonhospitalized patients. For hospitalized patients, colchicine is not recommended.

• There is not enough evidence to make a recommendation for or against use of fluvoxamine.

• The guidelines include information on variants of concern and their in vitro susceptibility to various monoclonal antibodies.

• The document also includes a new section on screening, triaging, and managing patients with mild-to-moderate COVID-19.