Guideline on Diagnosis and Management of Eosinophilic Esophagitis

The American College of Gastroenterology provides new, evidence-based recommendations to guide clinical care.

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder characterized by esophageal dysfunction (mainly dysphagia and food impaction) and eosinophil-predominant inflammation (usually ≥15 eosinophils per high-power field). EoE is currently considered the second-leading cause of chronic esophagitis and the leading cause of food impaction in young patients. Clinical implementation of consensus recommendations from 2007 and 2011 has been hampered by heterogeneous symptom presentations and disagreement on diagnosis and clinical endpoints for therapy.

In a new clinical guideline from the American College of Gastroenterology, researchers used the GRADE system to weigh the quality of evidence in making recommendations. Most recommendations…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors