CMV Viremia in HIV-Infected Patients in Thailand

In a retrospective study of patients starting ART at CD4 counts <200 cells/mm³, cytomegalovirus viremia was independently associated with increased 2-year mortality.

The effects of cytomegalovirus (CMV) infection on the course of treated AIDS patients in resource-poor countries remains poorly understood. In a recent retrospective study, researchers assessed CMV DNA levels in stored blood samples from 293 HIV-infected patients in Thailand who initiated or resumed ART between 1996 and 2010 at CD4 counts <200 cells/mm³.

Fifty-four percent of the patients were male, the median age was 33, the median baseline CD4 count was 82 cells/mm³, and the median HIV RNA level was 4.9 log copies/mL. Overall, 93% were treated with potent antiretroviral therapy (ART) regimens, and 7% received dual nucleoside reverse transcriptase inhibitor therapy. At baseline, CMV DNA was detected in 26% of the patients (median level, 548…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

CMV Viremia in HIV-Infected Patients in Thailand

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Reviewing Author