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Although Department of Health and Human Services guidelines recommend regular laboratory monitoring after antiretroviral therapy (ART) initiation, information is limited on the risk/benefit of long-term regular testing. To explore this issue, researchers using data from the Centers for AIDS Research Network of Integrated Clinical Systems cohort assessed laboratory abnormalities among HIV-infected adults who started ART between January 1, 2000, and January 31, 2010, in the U.S. Patients were included if they had normal baseline laboratory studies (lipid, hematologic, hepatic, and renal) and had at least one lab result after starting their first ART regimen. Modern ART was defined as a ritonavir-boosted protease inhibitor (PI), a nonnucleosid…