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Medications for toddlers and preschoolers are usually manufactured and prescribed as liquids. Researchers in Holland tested the acceptability and intake of four placebo oral formulations (4 mm round uncoated tablets, powder, suspension, and syrup) in 148 healthy young children (age range, 1–4 years). Each child received a different formulation twice on each of four days in random order. Parents were instructed to not pressure the children, and chewing of the tablets was neither recommended nor forbidden.
On a visual analogue scale of acceptability (range, 0–10 from very much unpleasant/bothersome to not at all unpleasant/bothersome), parents rated all four formulations high on the first day, with tablets significantly superior to the other f…