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Researchers defined risk factors for mortality from necrotizing soft-tissue infections (NSTIs) and developed a 30-day postoperative mortality risk calculator. Using a prospectively collected dataset of all patients undergoing surgical procedures at more than 500 academic and community hospitals from 2005 to 2010, researchers identified 1392 patients with ICD-9 codes for Fournier's gangrene, necrotizing fasciitis, and gas gangrene.
Median age was 55 years, 42% of patients were female, and median body mass index was 32 kg/m2. The most common procedures performed were debridement of NSTIs to the perineum, external genitalia, and abdominal wall. Multivariate logistic regression analysis identified 7 variables that predicted mortality: age >60 ye…