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For many patients with vitiligo, the primary objective of management is restoration of pigment to the vitiliginous plaques. But when the vitiligo is extensive, repigmentation may not be realistic, and depigmentation may be the best option. In times past, this could only be achieved with depigmenting chemicals. More recently, there have been reports that the same results could be achieved with Q-switched ruby (QSR) lasers. These authors conducted a retrospective evaluation of the long-term efficacy and safety of depigmentation using 694-nm QSR lasers in patients with extensive vitiligo.
Outcomes in 27 people with vitiligo seen at a single institution from 2000 to 2010 were evaluated. Response was assessed by comparing photographs taken before…