Skin-Fed Allergies

Exclusive breast-feeding does not prevent atopic dermatitis.

The relevance of food allergies to atopic dermatitis (AD) is debated. To prevent food allergies, many mothers feed breast milk only. This reasonable approach may not work. Allergic food sensitization may occur through contact of food with dermatitic skin.

Researchers examined 619 exclusively breast-fed 3-month-old infants for AD, scored any AD for severity, and screened for common mutations of the filaggrin FLG gene (which encodes the epidermal barrier protein filaggrin). They also performed skin-prick testing for allergy to six foods (cow's milk, egg, cod fish, wheat, sesame, and peanut).

About 25% had AD at examination. About 12% carried at least one FLG mutation (93% heterozygous, 7% either homozygous or compound heterozygous); in children…

Reviewing Author

Mark V. Dahl, MD

Disclosures

Consultant / Advisory board Ulthera, Inc.; AuBio LifeSciences, LLC; Paris Therapeutics

Equity Elorac, Inc.; Makucell, Inc.; Paris Therapeutics

Editorial boards UpToDate

Leadership positions in professional societiesNational Rosacea Society (Chairman, Medical Board)