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One of the holy grails for deep brain stimulation (DBS) research is to achieve a smarter and more efficient way to deliver electricity to the brain. To establish proof of principle for this type of approach in treating Parkinson disease (PD), researchers conducted an experiment on eight patients. They used a brain–machine interface that interprets brain signals in patients with advanced PD. The detected signals were used as a feedback to control the DBS lead, which was implanted in the subthalamic nucleus. Each patient had either adaptive DBS, continuous DBS, or random intermittent stimulation. The physiology derived from the local field potential (i.e., the pathological beta oscillation) was used as the trigger. Both blinded and unblinded …