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Large randomized, controlled trials of outpatient psychotherapy for adults with anorexia nervosa are rare. In this multisite, German study, researchers randomized 242 female outpatients (mean age, 28; illness duration of >6 years, 39%) to 10 months of focal psychodynamic therapy (FPT), enhanced cognitive-behavioral therapy (CBT-E), or optimized treatment as usual (TAU). Overall, 71% of participants had initial body-mass index (BMI) of 17.5 or under, 46% had binge-purge subtype, and 40% had at least one comorbid Axis I diagnosis, primarily mood and anxiety disorders. TAU helped patients gain access to experienced community therapists, educated their primary care physicians about eating disorders, and instructed them to conduct monthly weighi…