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Children with gastroesophageal reflux disease (GERD) are often diagnosed clinically, treated medically, and referred for surgical evaluation only after a 3- to 6-month trial of more-conservative therapy fails. To examine factors associated with surgical intervention, researchers conducted a retrospective cohort study of 141,190 children with GERD at 41 U.S. children's hospitals.
Antireflux procedures were performed in 8% of the cohort, and more than half (53%) of these children were age 6 months or younger. Children undergoing procedures were more likely to have Medicaid insurance, aspiration pneumonia, and failure to thrive than those who did not. Among many comorbidities associated with increased risk for undergoing a procedure, hiatal her…