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Individual case studies and small series have linked neoplasia with cutaneous vasculitis. Unlike a diagnosis of dermatomyositis, which prompts a search for malignancy, vasculitis has not traditionally prompted an evaluation for underlying cancer.
These authors retrospectively studied 16 patients with an underlying malignancy among 421 adults with cutaneous small vessel vasculitis treated at one Spanish medical center. (This 3.8% rate is similar to findings in other prior and smaller studies from other medical centers.) Patients with an associated malignancy were older than those without. Nine patients had a hematologic malignancy, including three with myelodysplastic syndrome and two with Waldenström macroglobulinemia. Seven patients had sol…