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Although the link between obesity and endometrial cancer is well established, how might intake of sugar-sweetened beverages (SSB) affect risk for this cancer? Beginning in 1986, researchers for the Iowa Women's Health Study assessed participants' health-related parameters such as dietary intake. Incidence of type I (estrogen-related) and type II (estrogen-independent) endometrial cancer was determined annually using state and federal surveillance data.
As of 2010, among 23,039 evaluable women (mean age at baseline, 62), 592 incident, invasive endometrial cancers were identified (506 type I, 89 type II). After adjusting for body-mass index and other confounders, placement in the top quintile for SSB consumption compared with the bottom quinti…