The Evidence on Photoprotection and Vitamin D

Vitamin D is a steroid hormone that is responsible for bone health. Its synthesis in the epidermis following ultraviolet B exposure has led to concern that sunscreens and other photoprotective measures may promote vitamin D deficiency. These authors reviewed the known evidence on this question.

They report high risk for vitamin D deficiency in patients with photosensitivity disorders (lupus, porphyria) or heavier pigmentation, breast-fed infants, people taking anticonvulsants and glucocorticosteroids, those who live farther from the equator or in areas with heavy pollution, and those with low sunlight exposure (elderly, home-bound, indoor workers). In the last class are medical resident, 26% of whom were vitamin D deficient in the fall, whil…