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Up to 3% of pregnancies are complicated by abnormal liver test results. In the minority of patients, such abnormalities indicate severe disease — most commonly preeclampsia and HELLP (hemolysis, increased liver enzymes, low platelets). To aid in risk stratification of these patients, investigators identified predictors of mortality in pregnant women admitted to a university teaching hospital in India for liver disease or jaundice between 2000 and 2011.
Using a retrospective design, researchers collected clinical, hematologic, and biochemical data and developed regression models to predict 1-month mortality. Follow-up data were available until death or 3 months after delivery.
Of 130 patients identified with pregnancy-specific liver disease, 3…