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In a Danish population-based study, researchers determined whether visible age-related correlated with risk for ischemic heart disease (IHD), myocardial infarction (MI), and death. Almost 11,000 white adults (free from known heart disease at baseline; 46% women) were followed from the mid-1970s through 2011.
During 35 years of follow-up, 3400 participants developed IHD, and 1700 suffered MIs. Even after adjustment for age and other clinical risk factors, frontoparietal balding, balding at the crown, earlobe creases, and xanthelasma all correlated with excess risk for IHD and MI. Risk for IHD and MI increased with increasing numbers of age-related signs (hazard ratios, 1.4 for IHD and 1.57 for MI for 3–4 signs vs. no signs at baseline). Conve…