Non-Hodgkin Lymphoma: Yet Another Reason to Control HIV Viremia

NHL incidence among HIV-infected patients remained increased despite treatment with antiretroviral therapy.

Although antiretroviral therapy (ART) has had a profound effect on many HIV-associated complications, AIDS-related non-Hodgkin lymphoma (NHL) remains an ongoing problem despite the potency of combination ART. Using data from the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort of HIV-infected adults in care at eight U.S. clinical sites, investigators examined NHL incidence and risk factors among 6036 treatment-naive patients who started combination ART between 1998 and 2009 and achieved suppression of HIV viremia to ≤500 copies/mL within the first year of starting treatment. (Patients who enrolled before 1998 were excluded to assure testing was done with ultrasensitive HIV RNA polymerase chain reaction assays.…

Reviewing Author

Charles B. Hicks, MD

Disclosures

Consultant / Advisory boardGilead Sciences; ViiV; Merck

RoyaltiesUpToDate, Inc.

Grant / Research supportNIH; Department of Health and Human Services

Charles B. Hicks, MD

Disclosures

Consultant / Advisory boardGilead Sciences; ViiV; Merck

RoyaltiesUpToDate, Inc.

Grant / Research supportNIH; Department of Health and Human Services

Non-Hodgkin Lymphoma: Yet Another Reason to Control HIV Viremia

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Reviewing Author