Extracorporeal Cardiopulmonary Resuscitation Is Associated with Improved Neurological Outcomes

Patients with out-of-hospital cardiac arrest who received a treatment bundle that included ECPR had better neurological outcomes at 1 and 6 months than those who received conventional resuscitation.

Extracorporeal cardiopulmonary resuscitation (ECPR) may improve cerebral perfusion, but is performed in only some facilities. To assess the effect of ECPR on neurological outcomes, researchers in Japan prospectively studied 454 patients aged 20 to 75 years with nontraumatic out-of-hospital cardiac arrest and initial ventricular fibrillation or pulseless ventricular tachycardia who arrived without pulses at 26 hospitals with ECPR capability and 20 hospitals without ECPR capability. ECPR was performed as part of a resuscitation bundle that also included therapeutic hypothermia and an intra-aortic balloon pump.

Favorable neurological outcome was defined as Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories scores of 1 or…

Reviewing Author

Kristi L. Koenig, MD, FACEP, FIFEM

Disclosures

Editorial boardsKoenig & Schultz's Disaster Medicine: Comprehensive Principles and Practices

Kristi L. Koenig, MD, FACEP, FIFEM

Disclosures

Editorial boardsKoenig & Schultz's Disaster Medicine: Comprehensive Principles and Practices

Extracorporeal Cardiopulmonary Resuscitation Is Associated with Improved Neurological Outcomes

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Reviewing Author