Children with Resolved Glomerular Disease at Risk for Adult Hypertension?

Many children with glomerulonephritis and nephrotic syndrome appear to have complete resolution of signs and symptoms of disease. To determine whether these children are at increased risk for subsequent hypertension in adulthood, researchers compared 37,880 men in the Israeli military with no history of glomerular disease at age 17 years and 264 military men with a history and physical exam compatible with resolved glomerular disease at age 17 years.

During a mean follow-up of 18 years (mean age, 36 years), 13.6% of men with histories of resolved glomerular disease developed hypertension versus 7.4% of those without such history (adjusted hazard ratio, 1.67). Mean values for body habitus, serum creatinine, and history of smoking did not diff…