Tau levels were correlated with concussion in the first 6 days in a group of hockey players.
Because concussion is currently diagnosed by clinical symptoms and self-report, researchers have sought “objective” markers of neuronal injury. In addition to findings from advanced imaging techniques, several biomarkers of glial and neuronal injury have been explored. These investigators prospectively studied changes in several biomarkers in blood — total tau (T-tau; a marker of axonal damage), S-100 calcium binding protein B (S-100B; a glial marker), and neuron-specific enolase (NSE; a marker of neuronal injury). Two authors are industry employees; two others have a related patent application.
Of 188 Swedish hockey players who participated, 35 sustained a concussion, and 28 had post-concussion blood samplings at 1, 12, 36, and 144 hours af…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)