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The default mode network (DMN), a network of regions including the medial prefrontal cortex, cingulate cortex, parietal cortex, and precuneus, mediates self-referential activity and moral judgment. Two new studies look at its role in psychopathy and depression.
Psychopathy is characterized by criminal behavior, lack of empathy, and reduced ability to learn from experience; this lower ability might be characterized by deficient processing of emotional information. Contreras-Rodríguez and colleagues used combined functional and anatomical neuroimaging to measure global gray-matter connectivity so that they could assess processing of emotional information in 22 men with serious criminal histories and 22 controls with neither criminal histories …