Cancer Trends in HIV-Infected People During the Era of Effective Antiretroviral Therapy

Cancer trends in HIV-infected people may be influenced by changes in group demographics (e.g., aging), in background rates of cancer in the general population, and in the relative risk for cancer in HIV-infected individuals compared with the general population. Now, investigators have used data from the HIV/AIDS Cancer Match Study, which links HIV and cancer registries in seven states, to examine how these factors have influenced time trends for 10 cancers in HIV-infected patients.

Data were evaluated for approximately 275,000 HIV-infected patients (~1,472,000 person-years of follow-up) for 1996 through 2010. During this period, the proportion of follow-up time contributed by people aged ≥50 increased from 13% in 1996–2000 to 27% in 2006–201…