Predictors of Adenoma Detection in U.K. Bowel Screening Program

In the U.K.'s bowel cancer screening program, patients undergo a nonrehydrated, guaiac-based, fecal occult blood test (FOBT), and those with positive results are referred for colonoscopy. In the current study, investigators used those program data to assess predictors of adenoma detection in 31,088 colonoscopies performed by 148 colonoscopists in FOBT-positive patients. The adenoma detection rate was 46.4%, and 28.9% had an advanced adenoma.

In multivariable analysis, patient-related factors predictive of any adenoma, advanced adenomas, and right-sided adenomas included male gender, older age, past or current smoking, and alcohol use. Procedural factors that were associated with improved detection of all adenomas, advanced adenomas, and righ…