Loading...
Patients with malignancies are at increased risk for venous thromboembolism (VTE), and when VTE does occur, cancer patients are more likely to have recurrences. However, giving anticoagulant prophylaxis to avoid new thrombotic events could be complicated by major hemorrhage. To estimate the risks for VTE recurrence and anticoagulant-associated bleeding, investigators studied 2316 patients without active cancer and 477 patients with active cancer residing in Olmsted County, Minnesota.
VTE recurred more often in patients with cancer than in those without cancer (cumulative recurrence rate at 1 year, 26.7% vs. 10.0%; P<0.001). Mortality was significantly worse among cancer patients with pulmonary emboli compared with those with deep vein thromb…