Cardiac Resynchronization Therapy in the Real World

National registry data support randomized-trial evidence that mortality and readmission rates are lower with CRT-D than with ICD alone.

Implantable cardioverter-defibrillators (ICDs) are recommended for many patients with reduced left ventricular ejection fractions. Cardiac resynchronization therapy with an ICD (CRT-D), involving placement of an additional lead in the coronary sinus, is recommended for ICD-eligible patients with heart failure (HF) and electrocardiographic evidence of ventricular dyssynchrony (QRS prolongation). To compare the effectiveness of the two devices in an unselected population, investigators studied data from the National Cardiovascular Data Registry's ICD Registry involving some 30,000 patients having first-time device implants in 1450 U.S. hospitals from April 2006 through December 2009. Propensity-score modeling resulted in a matched cohort of 3…

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Cardiac Resynchronization Therapy in the Real World

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Reviewing Author