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Gastrointestinal angiodysplastic lesions (GIADs) present a difficult diagnostic and therapeutic challenge. Although capsule endoscopy has increased the identification of these lesions, their long-term treatment remains suboptimal.
To examine the efficacy of treatments for GIAD, investigators performed a systematic review and meta-analysis of 22 studies comprising 831 patients. The endpoint was long-term bleeding cessation. Results were as follows:
Seventeen studies evaluated endoscopic therapy, which, although successful for initial hemostasis, resulted in a rebleeding rate of 34% (95% confidence interval, 27%–42%) during a mean follow-up of 22 months. When analysis was limited to the small bowel, the rebleeding rate was 45% (95% CI, 37%–52%)…