Henoch Schönlein Purpura — Observations from a Large Cohort in Northwest Spain

Characteristics and outcome after long-term follow-up

Henoch-Schönlein purpura (HSP), a small vessel vasculitis, is characterized by palpable purpura, nephropathy, arthritis, and gastrointestinal (GI) bleeding or colicky pain. More frequent in children, it also occurs in adults. Association with IgA deposition in tissue has been suggested but is not included among criteria for diagnosis, nor do authorities classify IgA deposition with cutaneous vasculitis as HSP, absent other findings.

These authors conducted long-term follow-up of a large cohort of patients with vasculitis. Included were 417 patients classified as having HSP per American College of Rheumatology (ACR) criteria. Three of the following criteria will lead to correct diagnosis of HSP 87.1% of the time: palpable purpura, bowel angin…

Reviewing Author

Jeffrey P. Callen, MD

Disclosures

Consultant / Advisory board XOMA; Eli Lilly; Celgene

Equity Various trust accounts

Editorial boards JAMA Dermatology; UpToDate

Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)